1. A co-formulant shall not be accepted for inclusion in a plant protection product where it has been established that:
its residues, consequent on application consistent with good plant protection practice, and having regard to realistic conditions of use, have a harmful effect on human or animal health or on groundwater or an unacceptable effect on the environment; or
its use, consequent on application consistent with good plant protection practice and having regard to realistic conditions of use, has a harmful effect on human or animal health or an unacceptable effect on plants, plant products or the environment.
2. Co-formulants which are not accepted for inclusion in a plant protection product pursuant to paragraph 1 shall be included in Annex III in accordance with the regulatory procedure with scrutiny referred to in Article 79(4).
3. The Commission may review co-formulants at any time. It may take into account relevant information provided by Member States.
4. Article 81(2) shall apply.
5. Detailed rules for the implementation of this Article may be established in accordance with the regulatory procedure referred to in Article 79(3).